CBD is one of the main cannabinoids of cannabis plants. We’ve all recently heard of different supplements and oils containing CBD as the active substance. While it’s regarded as an innovative and a new supplement, the history of CBD extraction dates back to more than 60 years. The successful extraction of pure CBD was first performed by a Harvard chemist, from the Sativa cannabis plant. Since the extraction itself wasn’t intended, but an accident, the chemist didn’t realize what it was that he stumbled on for a while. A few years later, the chemist and other scientists researched the nature of the CBD and how it affects the human body. Serious testing and research of CBD began in 1946 with official testing on animals. Tests came back with conclusive results, which stated that CBD doesn’t alter the mental state of the recipient.
Unlike THC, another vital cannabinoid, CBD doesn’t have any ‘high’ effect. Its use is mainly constricted in the medical and therapeutic fields. Before the CBD’s rise in popularity, people who had physical and psychological conditions relieved their pain by smoking cannabis or compounds made from a mix of THC and CBD. Transitioning to CBD helped those people enjoy the pain-relieving and anxiolytic effects of CBD without altering their mental state or perception. In this article, we’ll be discussing whether the use of the CBD is a healthy, wise choice.
Regulations and Evidence
CBD oil extracts are legal for recreational and medicinal purposes in 30 states, in addition to the 17 states that have CBD-specific laws. While the reported effects of CBD are positive in terms of relieving a wide array of psychological and physiological ailments, the evidence to support the claims isn’t enough to be conclusive. The production of CBD is under a very loose regulatory grip, which causes the products to vary drastically in quality. It is extracted in different ways to produce versatile products, about which you can find out more online. The purity of the products is also dependent on the vendor, so it’s a good idea to look for a reliable brand.
The main use of CBD—heavily supported by scientific evidence—is treating epilepsy, which made the FDA approved its use for the treatment of two rare forms of epilepsy. Other common uses are still not approved by the FDA due to a lack of conclusive evidence, but clinical trials of the CBD’s effects on anxiety yielded positive results.
CBD has been tested on animals for its potential use as an antidepressant, antipsychotic, and sleep aid. While quite a few animal studies were conducted, there hasn’t been enough testing on humans to provide useful evidence. Moreover, clinical trials on humans lacked the element of controlled comparison with groups that didn’t use CBD. The placebo effect has certainly made the job harder, and more intricate clinical studies are yet to be carried out. The FDA’s low rate of approval of the potential uses of CBD is currently complicating the regulation process in certain states, as they don’t have the FDA’s resources.
The use of marijuana in pain treatment dates back to 2900 B.C. What research has revealed is that the component in marijuana that mainly aids in pain relief is CBD. It affects endocannabinoid receptors, which regulate the functions like sleep, pain, and the immune system’s response to threat. CBD affects endocannabinoid receptors in a way that helps reduce inflammation and pain. Studies on lab rats show that CBD injections reduce the neurological pain response to surgical incision and sciatic nerve pain. A combination of THC and CBD is becoming popular around the world as a drug used to treat multiple sclerosis; it’s been approved in numerous countries.
Effect on Anxiety and Depression
The most common mental disorders in the world are anxiety and depression; they are usually chronic and have a big impact on a person’s quality of life. The World Health Organization concluded that the top condition leading to disability is depression, with anxiety ranked as the sixth. The reason CBD is becoming more popular for the treatment of these mental disorders is the negative side effects of pharmaceutical drugs. Most drugs designed to treat such disorders include powerful side effects like insomnia, drowsiness, sexual dysfunction, and other symptoms. With certain drugs, scarier symptoms can even include addiction and suicidal tendencies in some cases. CBD has shown positive results in treating anxiety, with no side effects. The anxiolytic and antidepressant-like effects were linked to the CBD’s impact on serotonin receptors and the increased production of this neurotransmitter.
Effect on Cancer-Related Symptoms
CBD is one of the most commonly prescribed medications for sufferers of cancer. It’s mainly used to alleviate the common side effects of cancer treatment, such as nausea, vomiting, and inflammation. Studies have been conducted on cancer patients who didn’t experience a lot of pain relief with common pain medication. The results were in favor of CBD since it significantly reduced the symptoms. It was also found to help treat common chemotherapy-induced ailments like vomiting and nausea. A study combined both THC and CBD to test the effects of oral administration, and it was concluded that using it carefully in conjunction with standard medication produces the best results. Another recent study found that CBD significantly combated the aggressive spreading of breast cancer cells in mice.
Studies and research on the CBD’s effect on blood pressure and circulatory system have found that it can benefit heart health. CBD can be used to rapidly treat high blood pressure symptoms by reducing it to avoid strokes, heart conditions, and other syndromes. A study was carried out to measure the effects of CBD against a placebo. Not only did the CBD administration reduce high blood pressure, but it also made the body more tolerant of stressful tests that reduced the amount of expected pressure.
While the regulation of CBD is still in murky waters, scientific evidence is tipping the scales in its favor. The main problem is being able to find a good source of high-quality CBD, as a lot of vendors are taking advantage of the loose regulatory process. It’s always advisable to follow safety procedures by not mixing it with other drugs, and consulting your healthcare provider first.